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This observation has raised concerns regarding suboptimal drug exposure, altered pharmacokinetics, and heightened inflammatory burden in obese patients, highlighting the potential need for dose optimization or alternative treatment strategies in this population ( The impact of BMI on treatment response is well illustrated by the AQUILA study, which examined real-world outcomes in PsA patients treated with ( However, the relationship between BMI and response to biologic therapies is not uniformly consistent across studies

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COVERAGE BY PLAN TYPE How Plan Type Affects Coverage How Plan Type Affects Coverage Your Aetna Wegovy coverage depends on your plan type: Most commercial plans: Wegovy is covered with prior authorization (preferred GLP-1) Self-funded employers: May have different formulariescheck with HR Medicare/Medicaid: Coverage is limitedsee specific guides Good News for Most Aetna Members Since July 2025, Wegovy is the preferred GLP-1 medication on CVS Caremark formularies